A recipient of a Certificate of Aptitude in cello pedagogy and a license in musicology from the Sorbonne, Gaillard has been teaching since 2000.

[1][2] In 1998, she won third prize in the International Johann Sebastian Bach Competition, and was voted "Revelation: Solo Instrumentalist of the Year" at the Victoires de la musique classique in 2003.

She is a recitalist and champion of the solo cello repertoire, from the Bach suites to contemporary music.

In 2005, Ophélie Gaillard founded Pulcinella, a chamber ensemble dedicated to playing Baroque music on period instruments.

[2] After a knifepoint robbery in Paris on 15 February 2018,[6] reported on Facebook, it was anonymously returned two days later.