Opisthorchiidae is a family of digenean trematodes.

Opisthorchiidae have cosmopolitan distribution.

[1] The most medically important species in the family Opisthorchiidae are Clonorchis sinensis, Opisthorchis viverrini, and Opisthorchis felineus,[1] that are causes of the disease clonorchiasis.

[1] Some species are parasites of economically important fish, e.g. Clarias gariepinus.

[2] Thirteen subfamilies are in the family Opisthorchiidae:[1] but their number is inconsistent:[1] The family Opisthorchiidae consists of 33 valid genera:[1]