[3] The cargo service, initially on charter basis, was carried out with a 45-ton payload capacity Airbus A300F-200 freighter aircraft between Istanbul and Gatwick, London, United Kingdom via Brussels, Belgium.
[1][6][7][8] In March 2004, a 105-ton payload capacity Boeing 747F-200 freighter jumbo jet joined the fleet servicing between Shanghai and Brussels via Istanbul.
[7] Cargo operations were extended to destinations including Almaty in Kazakhstan, Bishkek in Kyrgyzstan, Dhaka in Bangladesh, Hong Kong, Nanjing and Jiangsu in China.
[7] In March 2004, Orex became the first ever cargo airline carrying humanitarian aid during the intervention of an international peacekeeping force in Haiti after the 2004 coup d'état, which followed political unrest and rebellions.
On behalf of the United Nations, 25-ton of food, medicine and two ambulances were flown from Geneva, Switzerland to Haiti via Shannon, Ireland and Gander, Canada.