Its principal concert venue is the Auditorium du Nouveau Siècle, since 2003.
[1] In 1976, through the actions of the Région Nord-Pas-de-Calais and conductor Jean-Claude Casadesus, the orchestra was reformed as the Orchestre philharmonique de Lille.
In 1980, with government sponsorship, the orchestra took its current name, the Orchestre National de Lille.
[2] In March 2016, the orchestra announced the appointment of Alexandre Bloch as its next music director, effective with the 2016–2017 season.
[5] In October 2023, the orchestra announced the appointment of Joshua Weilerstein as its next music director, effective September 2024.