[1] The main hospital building, constructed in 1894, had formerly housed the Oregon State Deaf-Mute School.

After its conversion into the state tuberculosis hospital, multiple cottages and additional buildings were constructed on the property.

[1] On November 21, 1910 the first five patients were admitted to the Oregon State Tuberculosis Hospital, which housed a total of fifty beds.

[1] In 1934, a third floor was added to the main hospital, followed by a Nurses Home and several Physician Cottages.

[1] Due to overcrowding, an additional sanatorium was opened in The Dalles, followed by the University Tuberculosis Hospital in Portland in 1939.