He has previously played in Major League Baseball (MLB) for the Kansas City Royals and San Francisco Giants.

His father Dieudonne, emigrated to the Dominican Republic in 1977; obtained legal status and had several other children who also pursued baseball.

[3][4] Calixte began the 2015 season with the Omaha Storm Chasers of the Triple–A Pacific Coast League.

Calixte split the 2016 campaign between Northwest Arkansas and Omaha, hitting a combined .274/.324/.420 with 11 home runs, 43 RBI, and 19 stolen bases across 126 games.

[6] On November 14, 2016, Calixte signed a minor league deal with the San Francisco Giants.

[11] Calixte spent the 2018 campaign with the Triple–A Sacramento River Cats, playing in 125 games and hitting .270/.323/.405 with 11 home runs, 48 RBI, and 14 stolen bases.

[14] On April 19, 2021, Calixte signed with the York Revolution of the Atlantic League of Professional Baseball.