Orme stayed in training as a four-year-old and won another Eclipse Stakes, becoming the first horse to win the race twice, a feat that has only been repeated four times since.

"[5] Prior to Orme's first appearance on a racecourse, John Porter tested him over five furlongs against the three-year-old Massacre and three two-year-olds, including Orville.

Ridden by George Barrett, Orme won the trial by half a length from Massacre.

20/1 outsider Ben Avon led the field of eight in the early stages of the race, with Orme in the middle of the pack.

Dunure made some progress from the back of the field into second place, but none of the runners could get to Orme, who won by one length.

[12] He returned to racing against horses of his own age, starting the 8/15 favourite of a field of ten runners for the six-furlong Middle Park Plate at Newmarket.

[13] Orme then started in the Dewhurst Plate, but his presence deterred many owners from entering and he faced only two rivals.

[14][15] Orme's final race of the season came on 30 October in the Home-bred Foal Post Stakes over five furlongs and 140 yards at Newmarket.

[19] Going into the 1892 season Orme was a strong favourite for the Epsom Derby, with odds as short as 2/1 in December.

It was suspected that the culprit may have been a well-known backer of Derby rival La Fleche, with the poison being administered in a lozenge that Orme chewed, blistering his tongue.

Orme's trainer John Porter and Williams, the veterinary surgeon, remained convinced that he had been poisoned and was not just suffering from bad teeth.

He stated that the horse was fine on the morning of the 21 April, but a few hours later his tongue was so inflamed he could not hold it in his mouth; something so sudden, Lewis argued, could not have been caused by a decaying tooth.

He suggested that the poison may have in fact been attempted to be administered by some ball being put down his throat, but due to the struggles of the horse, it burst in his mouth, blistering his tongue.

[31] Porter ran Orme in a trial four days before the Eclipse Stakes at Sandown Park as preparation.

[4] In the Eclipse he faced six rivals and started the 5/4 favourite, with Sussex Stakes winner Orvieto next in the betting at 11/4.

[33] Orme had apparently improved significantly since Goodwood, and jockey George Barrett said, "I would stake my life he can beat Watercress 100 yards.

[36] In the race the early pace was slow, and Barrett positioned Orme near the front of the field.

[40] Two weeks later he faced Sir Hugo, Orvieto, El Diablo and Frank Marsh in the Limekiln Stakes at the Newmarket Houghton meeting.

Without even being asked for an effort, he won easily by three lengths from El Diablo, with Sir Hugo in third.

Bushey Park led in the early stages until Orme went into the lead with about two furlongs left to run.

El Diablo overtook Orme in the final 100 yards and beat him by one and a half lengths.

[43] Orme returned to the track as a four-year-old in the Rous Memorial Stakes at Royal Ascot.

[45] Orme and La Fleche met again in the Gordon Stakes at Goodwood with two other opponents, Watercress and Royal Harry.

Starting favourite, Orme had La Fleche in trouble with more than a quarter of a mile still to run.

He seemed to have the race won, but then veered left forcing Morny Cannon to pull him back and allowing La Fleche to draw level.

[47] During the autumn Orme's legs had started to give him trouble and during the Limekiln a suspensory ligament gave way.

[51] His first covering was St. Mary, a daughter of Hermit, which resulted in his first foal (a chestnut colt) being born in January 1895.

Orme's daughter Topiary was the dam of the St Leger and Eclipse winner Tracery.

Orme's daughter Optime was the dam of the American horse Sysonby, who was only defeated once in his career.

[3] Orme's sire line continues today mainly through Ajax's son Teddy.