Oro Grande (Spanish for "Large Gold") is an unincorporated community in the Mojave Desert of San Bernardino County, California, United States.

It is at 3,000 feet (910 m) elevation in Victor Valley north of the San Bernardino mountain range.

After the Americans acquired California in the Mexican American War, Mormon pioneers developed a wagon road from Salt Lake City to Los Angeles on the western part of the Old Spanish Trail crossing the Mojave River here just below the Lower Narrows of the Mojave River.

In 1880, other strikes found $2,000 a ton in silver and $18,000 per ton in gold to the southwest led to the organization of the Red Mountain Gold and Silver Mining District and the construction of the mining town of Oro Grande almost 2 miles below Lane's old crossing east of the river.

The first houses were built and a post office established called Halleck in January 1881.