The castle was formerly the residence of the Toledo family of nobles.

This includes Francisco de Toledo, Count of Oropesa, who became the Viceroy of Peru.

The town has a yearly celebration in April called "Jornadas Medievales", or "Medieval Days", which plays off the presence of the Castle in Oropesa.

The most accepted idea is its origin from the pre-Roman place name Otobesa.

This article about a location in the autonomous community of Castilla–La Mancha, Spain is a stub.