Orsenigo (Brianzöö: Ursenìgh [urseˈniːk]) is a comune (municipality) in the Province of Como in the Italian region Lombardy, located about 35 kilometres (22 mi) north of Milan and about 9 km (6 mi) southeast of Como.

Orsenigo borders the following municipalities: Albavilla, Albese con Cassano, Alserio, Alzate Brianza, Anzano del Parco, Cantù, Capiago Intimiano, Montorfano.