Ortuella is a town and municipality located in the province of Biscay, in the Autonomous Community of Basque Country, northern Spain.

Nowadays part of the Greater Bilbao region, until the beginning of the 19th century it was integrated in the Valley of Somorrostro of the Encartaciones next to the Santurtzi.

In 1901 the locality segregated from the Council of the Santurtzi, those days happening to denominate the Santurce-Ortuella.

In the 1980s, and by means of the resolution of 27 March 1981, the name of the municipality definitively lost the term "Santurce", simply being "Ortuella", which was the usual name used by their citizens.

Ortuella was the site of a deadly explosion at the Marcelino Ugalde Primary School on 23 October 1980 that killed 50 schoolchildren and 14 adults, and injured killed and injured an additional 128.