[4] She notably appeared as Melvyn Douglas' unfaithful wife dealing with blackmailer Joan Crawford in A Woman's Face (1941).

She also starred with Lloyd Bridges in the movie Rocketship X-M (1950), the first space adventure of the post-World War II era.

[citation needed] Later in her career, Massen appeared in guest roles on many television programs.

[1]: 229 Massen died on 2 January 2006, 11 days before her 92nd birthday, following unspecified surgery in Hollywood, California.

[5][note 1][6] Her remains are buried at Westwood Memorial Park in Los Angeles, California[3] with a plaque that lists her name as Osa Massen Vogel.