At 28 kilometres (17 mi) long, it is the longest monorail system in Japan.

Its mainline forms an arc through the northern and eastern suburbs of Osaka, and is the only rail transit link to Itami Airport.

IC cards can be used on the Osaka Monorail, including Suica, Pasmo, PiTaPa and ICOCA.

In 2015, Osaka Prefecture announced plans to extend the monorail to Uryudo in Higashiōsaka.

[3] As of 2024, geotechnical investigations have started and the extension is projected to open in 2033.