He previously held the position of Head of International Relations Department for Hamas and Chair of the Political Committee of the Palestinian Legislative Council.

However, he stated "There is an absence of any proof or evidence of Iranian financial support to Hamas, Islamic Jihad and other Palestinian factions who have established contacts with Iran.

[4] Hamdan has advocated Palestinian unity talks and in an interview with Al-Arabiya on May 20, 2009, he said "I understand that each of us [Hamas and Fatah] must set conditions to reach an agreement.

"[8][better source needed] During the 2023- war in Gaza Hamadan acted as a media representative for Hamas, appearing from Lebanon across multiple platforms and channels internationally for interview and comment across various issues.

[11][better source needed] In a 2014 interview which aired on the Hamas-affiliated Al-Quds TV channel as translated by MEMRI, Hamdan stated that "killing children...is engraved in the historical Zionist and Jewish mentality."

Hamdan asserted that the organisation MEMRI had edited and 'cut' his words in a selective manner taking them out of context, going on to remark that "we are not against Jews, we are against the Israeli occupation".