[4] Perkins made his Broadway debut in 1924 in the George S. Kaufman – Marc Connelly play Beggar on Horseback.

In the next 12 years, he appeared in 24 Broadway productions, including The Front Page and Uncle Vanya.

He appeared in 12 silent films, including Puritan Passions, before moving to talkies such as Scarface and Gold Diggers of 1937.

In every aspect of technical facility, he was peerless....I believed I could take the kind of art Osgood Perkins exemplified — externally clear action, controlled every minute at every turn, with gestures spare yet eloquent — and blend that with the kind of acting the Group was built on: intense and truly emotional, rooted in the subconscious, therefore often surprising and shocking in its revelations.

"[5] On September 21, 1937, Perkins died of a heart attack in his bathtub shortly after playing in a performance of Susan and God.