Osmanabad is well connected by railway to Mumbai, Pune, Daund, Kolhapur, Kurduvadi Junction, Miraj, Pandharpur, Latur, Parli Vaijnath, Parbhani, Nanded, Nagpur, Akola, Hyderabad, Nizamabad, Barshi, Bidar, Hyderabad & Udgir.

Before 2004, a narrow-gauge track connecting Latur to Kurduvadi was passing through Osmanabad district.

First train arrived at Osmanabad railway station was Mumbai–Osmanabad Express.

Nowadays, Osmanabad is well connected by rail to all important cities in Maharashtra and India.

This article about a railway station in the Indian state of Maharashtra is a stub.