Osmaniye is an electoral district of the Grand National Assembly of Turkey.

It elects 4 members of parliament (deputies) to represent the province of the same name for a four-year term by the D'Hondt method, a party-list proportional representation system.

Population reviews of each electoral district are conducted before each general election, which can lead to certain districts being granted a smaller or greater number of parliamentary seats.

Osmaniye became a province in 1996 and first directly elected members to parliament in the 1999 general election.

Osmaniye is the home town and parliamentary seat of the Nationalist Movement Party, Devlet Bahçeli.