Osona (Catalan pronunciation: [uˈzonə]) is a comarca situated in the central region of Catalonia, Spain.

The name Osona comes from Ausetans (Latin: Ausetani), a group of Iberian people who had their capital in Ausa (today Vic); the Romans called the area Ausone or Ausona.

This natural depression in the center of the region was carved by river Ter and its tributaries and makes up a big part of Osona's land.

It is surrounded by mountains: The Sub-Pyrenees, with Bellmunt mountain towering in the north, the Lluçanès (Pre-Pyrenees) to the north-west and Moianès high plateau in the West, the Montseny in the southeast and the Guilleries, located at the apex of the Catalan Transversal Range and the Pre-Coastal Range, in the east.

Long famous for its local sausages (especially fuet) and other pork derivatives, in recent years the area has become somewhat infamous for the pollution of its many waterways due to the factory farming of pigs and Dairy cattle.