Osorno la Mayor is located on the eastern edge of the province in a region called Tierra de Campos, 50 kilometers from the provincial capital Palencia.

The town is considered a crossroad for its location on the natural path from the northern plateau to the Bay of Biscay, and from Burgos towards León and Galicia.

Construction, public works projects, and services are booming due to Osorno la Mayor's proximity to two highways (Burgos-León and Palencia-Santander) that pass nearby and the rail lines that follow the same route.

Today only the town hall and some elements of the municipal church, such as the baptismal font and the baroque altar, attest to a past with artistic or historical interest.

The most prominent holidays in Osorno la Mayor are the celebration of Our Lady of Ronte, the Pilgrimage of St. Pantaleón and the festivities of San Miguel de los Santos, which is held on the first weekend of July.