Osvaldo "Ossie" Ocasio (born August 12, 1955) is a Puerto Rican former boxer who held the World Cruiserweight Championship from 1982 to 1984.

Attempting to become the first Hispanic to win the world Heavyweight championship, Ocasio was badly outclassed and was knock out in the seventh round.

The following year he travelled to the UK and made little effort against local prospect John L. Gardner, before collapsing without getting hit in the 6th round.

In 1986, he made a comeback, winning two fights including a 10-round decision over former world champion Dwight Muhammad Qawi in Atlantic City.

He attempted to regain his world championship against Evander Holyfield in Marseille, France, but lost by a knockout in 11 rounds.

In 1990 he dropped decisions to Tyrell Biggs and Bruce Seldon, then travelled to the UK for two fights losing and being the first opponent to take Lennox Lewis to the distance and scoring an upset when stopping Jess Harding in 8 rounds.