Oswaldo formed part of the team that participated in the 2010 InterLiga he played four games and scored a goal against Club América in the 3rd minute of the match, Heading the ball in the left side of the post.

on May 31, 2012, it was officially announced Oswaldo Alanís would join newly crowned champions Santos Laguna for the Apertura 2012 season.

During the 2012–13 CONCACAF Champions League Alanís and his team made it to the final against cross town rivals Monterrey the Match ended in a 4–2 loss for Santos.

Alanís made his return to the Copa Libertadores after a 4-year absence on February 11, 2014, against Arsenal de Sarandí winning the match.

Following prolonged negotiations, it was announced Alanís would stay with the club for the remainder of his contract, thus allowing him to play in the Clausura tournament.

His second international career goal was in a Hexagonal match against Honduras, where he scored a header from a corner kick in a 3–0 home victory for Mexico.