Otego Creek is a 32.7-mile-long (52.6 km)[2] tributary of the Susquehanna River in Otsego County, New York.

[3] Clark Brook flows into Otego Creek north of Hartwick.

Keyes Brook flows into Otego Creek south of Mount Vision.

After exiting Gilbert Lake it continues flowing southeast before converging with Otego Creek east of Laurens.

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