It was formerly the fifth-largest municipality in land area in Mexico at 17,189.7 square kilometres (6,637.0 sq mi),[2] occupying more than a third of the entire state.

The vegetation found in the municipality of Othon P. Blanco is mostly of medium forest, spanning most of the interior of the municipality and there are more representative plant species are the sapodilla, the ramon, the guayabillo and chaco, more isolated areas within the municipality is populated by high forest, where you can find the siricote, the palo de tinte and mahogany, to the southwest of the town are engaged in areas of rainfed agriculture and irrigation, the main crop of sugarcane, along with the Caribbean coast can be traced mainly mangroves.

For the protection of animal and plant species in Othon P. Blanco there are three zones of ecological reserve, the area of Protection of Flora and Fauna Uaymil located on the northeast coast of the territory, near Mahahual, and the Manatee Sanctuary in the Bay of Chetumal and the Biosphere Reserve Banco Chinchorro.

Located on the coast, the eco resort of Kabah-na offers only four cabins in a hexagon shape to circulate the air and thatched roofs which keep the interior temperature cool.

It consists of twelve cabins palm-thatched roofs, handmade furniture and decorated with Mexican accents.