As an amateur he won a silver medal for Canada at the 1987 Pan American Games, losing to Cuba's Angel Espinosa in the final.

He is a two-time North American Boxing Federation (NABF) middleweight title holder, as well as recognized for being the first black Quebecer to win a WBO championship.

[2] At 17 years old, Grant had won the Canadian Senior Amateur Boxing Championships (CSABC) in his weight division of 71 kilos (156.5 pounds).

[3] Later on, Otis competed at the 1987 Pan American Games, earning a silver medal by being defeated in the finals against Cuba's Angel Espinosa, before turning pro.

After his second knock down in the 10th round, Grant's trainer Russ Anber threw in the towel, giving Jones Jr. the TKO victory.

[6] Following Grant's near-fatal car crash in 1999, doctors stated that although his superb condition saved his life,[6] he would be unable to continue boxing.

Grant continued his winning streak for another straight 6 fights, until he faced off against Librado Andrade (23-0) in 2006 for the WBC Super Middleweight number 1 contender position.

[2] Other injuries sustained during the crash included five broken ribs, a punctured lung, and a shattered shoulder blade, all on his left hand side.

The Otis Grant & Friends is a non profit charity, established in 1999, initially formed to aid hunger, poverty and sicknesses within the community.