[4] Moshfegh's subsequent novels include My Year of Rest and Relaxation, Death in Her Hands, and Lapvona.

[9] During her MFA study at Brown, she taught undergraduates, including Antonia Angress, author of the 2022 novel Sirens & Muses.

[17] In the book, Eileen, the protagonist and narrator, describes a series of events that occurred years ago, when she was young and living in a Massachusetts town that she calls "X-ville."

At the beginning of the novel, she is working as a secretary at a local juvenile prison while living with and caring for her abusive father, a retired police officer with alcoholism and paranoia.

[18] On July 10, 2018, Penguin Press published Moshfegh's second novel, My Year of Rest and Relaxation.

The book describes a young art history graduate living in New York City over 15 months from mid-June 2000.

Also in 2018, Moshfegh wrote a piece for Granta in which she describes an experience she had with a much older male writer when she was 17 years old.

[23] Moshfegh co-wrote the 2022 drama film Causeway with her husband, Luke Goebel, and Elizabeth Sanders.