It was built in 1856-57 by the Society of Jesus, and is now in the Knowsley deanery of the Archdiocese of Liverpool.

[2] It is a Grade II listed building, designed by Joseph Aloysius Hansom, and is next to the Church of St Mary on Vicarage Place in the centre of Prescot.

The Catholics were so numerous, that in 1583 the Bishop of Chester, William Chaderton, wrote to the Privy Council: Truly the Papists in these parts are lately growing so stubborn and contemptuous that in my opinion it were very requisite that their Lordships did write a very earnest letter to my good Lord the Earl of Derby, myself, and the rest of Her Majesty's Commissioners ... to deal seriously and roundly with them (the Papists of Prescot) otherwise there can be no reformation.

[3] In 1856, six years after the restoration of the English Catholic hierarchy and the creation of the Archdiocese of Liverpool, the Jesuits founded a church in the centre of Prescot and asked Joseph Aloysius Hansom to design it for them.

There are weekday Masses at 12.00pm on Monday, Wednesday, Friday and Saturday.