Ouzouer-sur-Trézée (French pronunciation: [uzwɛʁ syʁ tʁeze; uzwaʁ-]) is a commune in the Loiret department in north-central France.

The Briare Canal and the river Trézée run through the town.

A well-known mayor of the town was the French Resistance fighter and spy Count Robert de La Rochefoucauld

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