Pătârlagele (also spelled Pătîrlagele; pronounced [pətɨrˈlad͡ʒele]) is a town in Buzău County, Muntenia, Romania.

Pătârlagele is located in the western part of the county, along the national road DN10 connecting Buzău and Brașov.

It lies in the Pătârlagele hollow, between the Carpathian Mountains and the Subcarpathian Hills.

The town administers fourteen villages: Calea Chiojdului, Crâng, Fundăturile, Gornet, Lunca, Mănăstirea, Mărunțișu, Mușcel, Poienile, Sibiciu de Sus, Stroești, Valea Lupului, Valea Sibiciului, and Valea Viei.

The German origin of the name can only be explained by the presence of the Teutonic knights on the other side of the Carpathians, in Burzenland, during the years 1211–1225 and their conquest of the Buzău Mountains, where they raised fortifications against the Cumans.