Liprin-alpha-1

1N7F8500233977ENSG00000131626ENSG00000288198ENSMUSG00000037519Q13136n/aNM_003626NM_177423NM_001378006NM_001033319NM_001195086NP_003617NP_803172NP_001364935n/aLiprin-alpha-1 is a protein that in humans is encoded by the PPFIA1 gene.

Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development.

This protein binds to the intracellular membrane-distal phosphatase domain of tyrosine phosphatase LAR, and appears to localize LAR to cell focal adhesions.

Alternatively spliced transcript variants encoding distinct isoforms have been described.

[7] Protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 has been shown to interact with: This article on a gene on human chromosome 11 is a stub.