The PTRS-41 (Russian: Противотанковое самозарядное ружьё образца 1941 года системы Симонова, romanized: Protivotankovoye samozaryadnoye ruzhyo obraztsa 1941 goda sistemy Simonova, lit.

'Anti-tank-self-loading gun pattern 1941, Simonov system')[4] is a World War II-era semi-automatic anti-tank rifle firing the 14.5×114mm cartridge.

The gas-operated PTRS has a tendency to jam when dirty, and the 14.5mm cartridge produces significant residue, blocking the gas port.

Along with his partner Vasily Degtyaryov, Sergei Gavrilovich Simonov helped the Soviet Union develop new weapons between the First and Second World War.

[7] Although the PTRS-41 anti-armour capabilities quickly diminished after its introduction in 1941 to due increasing thickness of German tank armour, the 14.5×114mm round was still useful against soft-skinned targets such as trucks and in urban warfare.