A broad range of artists contributed to the album, including Outlawz, Krayzie Bone, Snoop Dogg, Chamillionaire, Ludacris, A-3, Big Syke, Papoose, Keyshia Cole, Jay Rock, Young Buck, Ashanti, T.I., Lil' Scrappy, Nipsey Hussle, three posthumous appearances by Kadafi, and Jamal Woolard, who became famous for portraying The Notorious B.I.G.

The World Premiere of "Pac's Life" was on at 7:30 PM on BET's Access Granted on Wednesday, November 22.

The events were then shifted to the Tupac Amaru Shakur Center for the Arts (TASCA) where coat drives were held on Wednesday, November 15 and Friday, November 17 everyone who brought a winter coat received two admission tickets to the Pac's Life album release party.

Reviews from critics and fans were mixed, with the general consensus being that while 2Pac's vocals were undoubtedly strong, the modern production sounded commercialized.

AllMusic wrote: "This isn't to say that there is not some great material on Pac's Life, because there is ..., but the power of 2Pac's words is often lost behind the modern production ... and new verses from artists like Ludacris, Lil Scrappy, Ashanti, and Young Buck.