Some of the native plant species present in the reserve are: Spondias mombin, Quararibea cordata, Mauritia flexuosa, Parinari excelsa, Cedrela odorata, Ocotea spp., Myrciaria dubia, Socratea exorrhiza, Calathea allouia, Solanum sessiliflorum, Hevea guianensis, Pouteria caimito, Clidemia hirta, Ficus maxima, Heliconia psittacorum, Inga spp., Psychotria poeppigiana, Alibertia edulis, Victoria amazonica, Ceiba pentandra, Phytelephas macrocarpa, Clusia spp., Swietenia macrophylla, Asclepias curassavica, Pachira aquatica, Cragious Psychotria, etc.

[3] Mammal species found in the reserve include: the Amazonian manatee, the red-faced spider monkey, the South American tapir, the Bolivian squirrel, the Amazon river dolphin, the puma, the giant otter, the white-lipped peccary, the jaguar, the red brocket, the tucuxi, the South American coati, the capybara, etc.

[2][4] Some species of fish found in the reserve are: Arapaima gigas, Pseudoplatystoma fasciatum, Phractocephalus hemiliopterus, Colossoma macropomum, Osteoglossum bicirrhosum, Potamotrygon motoro, Brycon melanopterus, Hyphessobrycon erythrostigma, Plagioscion squamosissimus, Prochilodus nigricans, etc.

[2] Birds found in the reserve include: the Spix's guan, the black-bellied whistling duck, the king vulture, the crimson-crested woodpecker, the harpy eagle, the blue-and-yellow macaw, the scarlet macaw, the black-throated mango, the horned screamer, the cobalt-winged parakeet, the swallow-tailed hummingbird, etc.

[2] The reserve has 15 authorized campsites distributed in 8 areas open for tourism; as well as 5 wilderness huts.