The Padas River (Malay: Sungai Padas) is a river in Interior Division, southwestern Sabah of Malaysia.

It has a total length of 120 km (75 miles) from its headwaters in the mountains of northwest Sabah to its outlet at the South China Sea, southwest of Beaufort town.

It originates from the Long Pasia in Sipitang and goes through the mountains in the interior Beaufort, Keningau and Tenom Districts, which are part of the Crocker Range system.

The river is important to provide water supply to Labuan and both districts of Beaufort and Tenom including as the main source of hydroelectric power to entire west coast of Sabah.

This article related to a river in Malaysia is a stub.