Padillasaurus is an extinct genus of titanosauriform sauropod known from the Early Cretaceous (Barremian stage) Paja Formation in Colombia.

[2] The fossil was discovered by local farmers in a limestone nodule during the 1990s in Ricaurte, northeast of Villa de Leyva.

Padillasaurus was originally described and named by José L. Carballido, Diego Pol, Mary L. Parra Ruge, Santiago Padilla Bernal, María E. Páramo-Fonseca y Fernando Etayo-Serna in 2015.

Although fragmentary remains of possible brachiosaurids are known from the Jurassic of Patagonia in Argentina,[3] Padillasaurus it is the first member officially named from South America.

Because of the few remains found is difficult to determine what would have been its body size, but may have had between 16 and 18 meters long and weigh about 10 tonnes.

The species shows some typical basic features of Titanosauriformes: the vertebra is opisthocoelic, with a convex front section and the back concave.

Unlike Cretaceous brachiosaurids from North America, in which the spinous process of the caudal vertebrae leaned slightly forward, those of Padillasaurus were angled rearward.