[1] Palakkad gap has played a major role in enabling human migration into Kerala from parts of Tamil Nadu.

[6][7] The gap affects the weather patterns in Southern India as it allows the moisture-laden Southwest monsoon winds into western Tamil Nadu, moderating summer temperatures and generating greater rainfall in the region relative to the rest of lowland Tamil Nadu.

It affects rainfall activity in parts of western Tamil Nadu, around Coimbatore, Palladam, Kangeyam, Dharapuram, Udumalai by allowing moisture laden winds from the West Coastal region of Kerala and Arabian Sea.

It is an important mountain pass in the Western Ghats that runs along the entire eastern edge of Kerala isolating it from the neighboring Tamil Nadu.

[9] Large windmill farms can be seen in and around Kanjikode, Chittur, Muthalamada, Kollengode, Pollachi, Kinathukadavu, Udumalaipettai, Dharapuram and Madathukulam.