The absolute symmetry conceived by the unknown architect who oversaw its construction characterises both the facades, the floor plan and the gardens, as can be seen in the surveys made by Rubens for the 1622 edition of the Palazzi di Genova.

Inside the west wing at number 10, the frescoed decoration, dated 1624 and the work of Lazzaro Tavarone, celebrates on the Vault of the atrium a war feat of Antoniotto Adorno, the owners' ancestor doge.

In the room on the piano nobile, also by Lazzaro Tavarone, is the fresco depicting the Deeds of Doge Antoniotto Adorno for the liberation of Pope Urban VI besieged by Charles III, King of Naples at Nocera (1385).

Other rooms present encomiastic subjects (Raffaele Adorno conquers the island of Gerba in 1388) biblical (Announcement of the angel to Hagar and Ishmael, Stories of Daniel) and mythological (Cupid blindfolded).

[4] In other living rooms under vaults frescoed with mythological subjects, precious furniture and knick-knacks are preserved, as well as part of the rich and well-known picture gallery comprising remarkable paintings between the XVI and the 17th century.