The Palazzo Vidoni-Caffarelli is a palace at the intersections of Via del Sudario, Piazza Vidoni, and Corso Vittorio Emanuele in the rione Sant’Eustachio in Rome.

The home has successive layers where the degree of facade decoration matches the function of the interiors.

The Palazzo Vidoni-Caffarelli conserves 16th-century frescoes in its Charles V hall that depict events in the life of the emperor.

The palace also contains some 18th-century frescoes attributed to Nicola Lapiccola, Bernardino Nocchi, Tommaso Conca, Ludovico Mazzanti.

It also contains a marble portal decoration of the Venetian lion of St Mark from a Croatian city.