Palermo is a census-designated place (CDP) in Butte County, California, United States.

According to the United States Census Bureau, the CDP has a total area of 29.2 square miles (76 km2), of which, 99.95% of it is land and 0.05% is water.

[6] The town was named after Palermo, Sicily due to its excellent climate for growing olives.

[7] The area was home to a country club, two railroad stations, gold mining, a brick yard, library, general mercantile store, school and even a semi-pro baseball team.

The rich clay soil attracted the planting of olive and orange orchards and a thriving zucca melon industry.

Mining magnate George Hearst purchased 700 acres in 1888, and then subdivided.

[8] In December 2024, a disgruntled man experiencing mental illness and homelessness opened fire at the town's Seventh-Day Adventist school, seriously wounding two children before killing himself.

416 households (21.4%) were made up of individuals, and 184 (9.5%) had someone living alone who was 65 years of age or older.

19.4% of all households were made up of individuals, and 9.0% had someone living alone who was 65 years of age or older.