Palestine is a village in Darke County, Ohio, United States.

It has always been a small community, although its population declined during the twentieth century; the 1910 census recorded 216 residents.

[4] According to the United States Census Bureau, the village has a total area of 0.15 square miles (0.39 km2), all land.

The racial makeup of the village was 93.5% White, 5.0% African American, and 1.5% from two or more races.

29.1% of all households were made up of individuals, and 8.9% had someone living alone who was 65 years of age or older.

14.0% of all households were made up of individuals, and 7.0% had someone living alone who was 65 years of age or older.