Palestine High School is a public high school located in Palestine, Texas (United States) and classified as a 4A school by the UIL.

It is part of the Palestine Independent School District located in central Anderson County.

The old Palestine High School built in 1915 is now The Museum for East Texas Culture.

[1] The school received an overall rating of "B" from the Texas Education Agency for the 2021–2022 school year.

This article about a high school in Texas is a stub.