Since 2020 there is proposed state legislation to restrict building heights that would rise above the cliffs on the eastern side of Palisade Avenue along the entire corridor from Jersey City to Fort Lee.

Two historic office buildings, one formerly PSE&G, and another now used North Hudson Community Action Group[12] are at the intersection,[13] at the end of which is Pohlmann's Hall.

The Main Post Office at the intersection with marginal road of 495 is a major stop for east-bound buses travelling to Manhattan.

At the northern end of the borough the avenue passes the former site of Palisades Amusement Park, demolished in the 1970s for the construction of high-rise residential complexes.

[24][25][26] After crossing Main Street, at the Barrymore Film Center, it passes the Modern higrise complex and ends at GWB Plaza, just west of Palisades Interstate Park and the George Washington Bridge.