She began her musical career in 2018, and her first studio album, Sueños de Dalí, was released in March 2021.

[3][4] She chose her stage name, Paloma Mami, in high school, inspired by Drake's Instagram username.

[5] After her parents separated, Castillo, alongside her mother and sister, moved to Santiago, where she began her musical career.

[6][7][8] Castillo was a participant in the first season of the Chilean talent show, Rojo, el color del talento, on Televisión Nacional de Chile.

[15] She cites several people as influences, including Bad Bunny, Rihanna, Christina Aguilera, Amy Winehouse, Aaliyah and Ella Fitzgerald.