Pamela Bjorkman

[6] As an undergraduate student, Bjorkman completed lab work with Larry Church at Reed College and O. Hayes Griffith at the University of Oregon.

[5] She stayed on in Wiley's lab in a postdoctoral position where she ultimately solved the first crystal structure of an MHC protein—the HLA-A2 human histocompatibility antigen.

[8] Bjorkman continued her postdoctoral research at Stanford University in Mark Davis’ laboratory, studying the T-cell receptors that recognize antigens presented in the binding groove of MHC proteins.

[4] The Bjorkman Laboratory at Caltech focuses on investigating immune responses to viral pathogens with the ultimate goal of improving therapeutics and contributing to vaccine development.

Bjorkman's research also focuses on engineering antibody reagents[5] and the development of mosaic nanoparticles for use in broadly effective vaccines.

HLA-A2 molecule; peptide antigen groove (starred) on top domain