The Panama City Fliers were a minor league baseball team based in Panama City, Florida, that operated in the Alabama–Florida League.
They were founded in 1951 as an affiliate of the Detroit Tigers.
In 1958, they were affiliated with the San Francisco Giants and they ended up as an affiliate of the Los Angeles Dodgers.
The team won league championships in 1955 and 1957.
From 1936 to 1939, the Panama City Pelicans played also in the Alabama–Florida League.