Amongst its first athletes were Giorgos Kalafatis, Apostolos Nikolaidis, Loukas Panourgias and Michalis Papazoglou.

In the 1928 Summer Olympics the athlete of the team, Antonis Kariofilis, became the first Greek to open the parade of nations.

After World War II, a strong team was created with Giannis Lambrou, Rigas Efstathiadis, Antonis Tritsis and others.

In the 1960s the great pole vaulter Christos Papanikolaou also joined the team.

Through the next decades Panathinaikos won many Championships, in both men and women, becoming one of the strongest teams in the country.