Pankrushikhinsky District (Russian: Панкруши́хинский райо́н) is an administrative[1] and municipal[4] district (raion), one of the fifty-nine in Altai Krai, Russia.

It is located in the northwest of the krai.

The area of the district is 2,700 square kilometers (1,000 sq mi).

[2] Its administrative center is the rural locality (a selo) of Pankrushikha.

[7] The population of the administrative center accounts for 36.8% of the district's total population.