On July 22, 2020, the NLL awarded an expansion franchise to the city of Fort Worth and owner Bill Cameron.

Although an intended insult, the name Panther City was enthusiastically embraced by locals after Fort Worth recovered economically.

[6] A week later on December 10, the franchise played its first ever home game at Dickies Arena, where they fell to the Vancouver Warriors, 14–8 in front of 7,309 fans.

[7] After five games, Panther City got their first franchise win on January 15, 2022, on Long Island against the New York Riptide, 13–12 thanks to an overtime goal from rookie forward Patrick Dodds.

A home loss to Saskatchewan closed out the year, though Panther City still posted the best inaugural season record by an expansion team since the San Diego Seals in 2018–19.