[1][2] On 3 October 2016, she was nominated rector of Libera Università Internazionale degli Studi Sociali Guido Carli.

Later she began to work at Perugia University and taught penal commercial law at the Faculty of Economics.

In addition, Severino worked with Giovanni Maria Flick, former President of the Italian Constitutional Court.

[5][6] Other prominent individual clients of Severino include Cesare Geronzi and Francesco Caltagirone whom she defended in the Cirio trial.

[8] Before her appointment as minister of justice, she was working as a professor of penal law at the School for Carabinieri Officers and a Pro-Rector Vicar at LUISS Guido Carli University.