The station has Amtrak and SEPTA ticket offices, a waiting room, vending machines, restrooms, and a coffee shop.

This one-story, tan brick building was constructed by the Pennsylvania Railroad in 1953 at a cost of $140,000; it replaced an earlier Victorian depot that was built in 1893.

[10][11] The first phase, which cost $48 million, made the station compliant with the Americans with Disabilities Act by replacing the two low-level side platforms with a high-level island platform, constructing a pedestrian overpass over the tracks, and adding elevators and ramps.

A ribbon-cutting ceremony for the first phase of the project was held on September 23, 2019, with Amtrak and SEPTA officials, disability rights groups, and area politicians in attendance.

[12] The canceled light rail Greenline would have connected Paoli station with the towns of Phoenixville and Oaks, Pennsylvania.