Paolo Canè (born 9 April 1965; Italian pronunciation: [ˈpaːolo kaˈnɛ]) is a former tennis player from Italy.

Canè turned professional in 1983.

During his career, he won three top-level singles titles (Bordeaux in 1986, Båstad in 1989, and Bologna in 1991) and achieved much success at the Olympics, reaching the semi-finals in 1984 (when it was a demonstration event) and the quarter-finals in 1988.

Canè's career-high rankings were World No.

He retired from the professional ATP Tour in 1995.